Archibald Huston begins another term as County Sheriff. John Hawkins and Moses Scott are his deputies.

• Big Bone Lick is deeded by David Ross to Wilson Allen, Edmund W. Rootes, and Jacob Myers, to discharge a debt of $14,000 plus interest, though Ross retained possession until 1 August.

• The Bank of Kentucky is organized. Forty-six new banks are chartered and are authorized to issue paper money.
• Shakertown at Pleasant Hill is established.
• Thomas Lincoln and Nancy Hanks, future parents of President Abraham Lincoln, marry in Springfield, Kentucky.

• American explorer Zebulon Pike identifies the Colorado peak that will eventually bear his name.
• Noah Webster publishes The Compendious Dictionary of the English Language. The volume rapidly becomes the recognized authority on American English.

• Boone County Tax Lists, 1806.