John P. Graves is Sheriff.

• Lewis Webb, Leonard Stephens and county surveyors are appointed to mark the line between Boone and Kenton counties.
• The name of the town of Landing is changed to Hamilton, in honor of Joel Hamilton.
• A road is put through from Carlton's Ferry on the Ohio River to Union, and then to the Covington-Lexington Turnpike.

• Radical temperance advocate Carrie Nation is born in Garrard County, Kentucky.

• Failing in his attempt to purchase the New Mexico territory from Mexico, President James Polk orders Zachary Taylor to advance to the Rio Grande. Congress declares War on Mexico.
• The U.S. and Britain sign the Oregon Treaty, demarcating the northwest border and ending calls for war with Britain.
• Brigham Young leads his Mormon followers west, outside what was then the U.S. border.

• Boone County Tax Lists, 1846: District 1, District 2.